Quartromicin, a complex of novel antiviral antibiotics. I. Production, isolation, physico-chemical properties and antiviral activity.

نویسندگان

  • M Tsunakawa
  • O Tenmyo
  • K Tomita
  • N Naruse
  • C Kotake
  • T Miyaki
  • M Konishi
  • T Oki
چکیده

A strain of Amycolatopsis orientalis No. Q427-8 (ATCC 53884) was found to produce a complex of new antiviral antibiotics, quartromicin which consisted of at least six components A1, A2, A3, D1, D2 and D3. Structural studies suggested that they are a novel type of molecules unrelated to any known antibiotics. Each component of quartromicin exhibited antiviral activity against herpes simplex virus type 1, influenza virus type A and human immunodeficiency virus.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 45 2  شماره 

صفحات  -

تاریخ انتشار 1992